Rogue lipids: How routine cellular stress can fuel chronic inflammation

AI Summary

A comprehensive review examines how oxidized lipids can either reduce or intensify systemic inflammation. The findings highlight how cellular stress and reactive fat molecules may contribute to chronic inflammatory processes.

Oxidized lipids—fats structurally altered by enzymes, oxygen or free radicals—are double-edged swords that can both quell and ignite systemic inflammation, according to a new comprehensive review aimed at sharpening the overall understanding of an intricate class of highly reactive molecules.