Scientists overcome key barrier to self-amplifying vaccines

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Researchers at Queen Mary University of London report a method to counter cells’ natural defenses against self-amplifying mRNA vaccines. The approach enabled cells to produce substantially more of the vaccines’ target protein, with findings published in Nature Communications.

Scientists at Queen Mary University of London have found a way to overcome cells' natural defenses against self-amplifying mRNA vaccines, allowing the cells to produce significantly more of the target protein. The findings are published in Nature Communications.