New treatment reduces heart scarring and abnormal heart rhythms, offering a possibility for future therapies

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A study led by Baylor College of Medicine and the University of Oxford found that blocking a molecular interaction reduced heart scarring and abnormal rhythms in mouse models and human cells. The researchers say the results could inform future therapies for atrial fibrillation, but the findings are not yet an established treatment.

In a study led by Baylor College of Medicine and the University of Oxford, researchers found that blocking a specific molecular interaction reduced atrial fibrosis in mouse models and cells from human patients with atrial fibrillation (AF), reduced fibrotic responses in human cells, and in the mouse models reversed established atrial fibrosis and reduced abnormal heart rhythms.