New analysis explains why bone marrow cancer T cells may need therapeutic activation

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Researchers from German Cancer Research Center and partnered institutes have studied T cells in bone marrow of patients with multiple myeloma and acute myeloid leukemia. Their findings, published in Cancer Cell, suggest that therapeutic activation of these T cells may be necessary for effective treatment.

A team led by researchers from the German Cancer Research Center (DKFZ), the HI-STEM Stem Cell Institute, and Medical Clinic V at Heidelberg University Hospital (UKHD) has characterized T cells in the bone marrow of patients with multiple myeloma and acute myeloid leukemia. The work has been published in Cancer Cell.