'Living medicine' tackles drug-resistant biofilms growing on ventilation tubes

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Researchers report that an inhaled genetically modified bacterium thinned antibiotic-resistant Pseudomonas aeruginosa biofilms in the lungs of pigs. The experimental treatment targets biofilms associated with endotracheal tubes used in hospitals.

A "living medicine" has thinned biofilms of antibiotic-resistant Pseudomonas aeruginosa in the lungs of pigs, according to the findings of a study published in the journal eBioMedicine. The experimental treatment involves inhaling a genetically modified bacterium designed to target layers of drug-resistant Pseudomonas aeruginosa that grow on the surfaces of endotracheal tubes used in hospitals.