HIV-1 signalling remodels nuclear pores to licence infection

AI Summary

Research highlights the role of HIV-1 in modulating nuclear pore complexes to enhance infection processes in host cells. This study may contribute to a deeper understanding of HIV pathogenesis and potential treatment pathways.

We propose that HIV-1 has evolved to selectively activate CD4 signalling during cell–cell spread to regulate infection at the step of the NPC, ...