American Cancer Society updates prostate cancer screening guideline: Regular PSA testing for average- and high-risk men

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The American Cancer Society has updated its prostate cancer screening guidance, recommending PSA testing every two years for average-risk men aged 50–69. It recommends annual screening from age 45 for Black men and men with a strong family history, with clinicians discussing potential benefits and harms before testing.

The American Cancer Society (ACS) today released an updated guideline for prostate cancer screening to help find cancer before it spreads and reduce the risk of dying from the disease. Key changes include a direct recommendation for prostate-specific antigen (PSA)-based screening every two years for average-risk men aged 50–69, with clinicians ensuring patients understand the potential benefits, limitations and harms before starting screening. Also, ACS recommends annual PSA-based screening beginning at 45 years old for Black men and men with a strong family history of prostate cancer.